Yes — under federal law, ICE agents can use deadly force, including shooting, if they reasonably believe a person is posing an immediate threat of death or serious bodily harm, such as trying to run them over with a vehicle
ICE officers follow the same use‑of‑force standards as other federal law enforcement, including the FBI and DEA. The governing legal framework comes from the 1989 Supreme Court case Graham v. Connor, which set the “objectively reasonable” standard: a court will assess whether a reasonable officer, with the same information, would have acted that way in the split second
Minneapolis, Minnesota (Jan 2026): An ICE agent shot and killed Renee Good after her SUV moved toward agents during an immigration operation; DHS defended it as self‑defense
Bottom line: ICE agents can legally shoot someone attempting to run them over if they reasonably believe it poses an immediate threat of death or serious injury, but such actions are subject to strict legal review and public scrutiny